3-Aminoquinuclidine → HCID 15616385, compound

HRID 703418Notes

Reaction equation

HRID 703418 reaction equation
[NH2:1][CH:2]1[CH:7]2[CH2:8][CH2:9][N:4]([CH2:5][CH2:6]2)[CH2:3]1.[CH2:10]([O:12][C:13]1[CH:23]=[CH:22][CH:21]=[CH:20][C:14]=1[C:15]([N:17]=[C:18]=[O:19])=[O:16])[CH3:11].C([O-])(=O)/C=C/C([O-])=O>>[N:4]12[CH2:9][CH2:8][CH:7]([CH2:6][CH2:5]1)[CH:2]([NH:1][C:18]([NH:17][C:15](=[O:16])[C:14]1[CH:20]=[CH:21][CH:22]=[CH:23][C:13]=1[O:12][CH2:10][CH3:11])=[O:19])[CH2:3]2

Participants

4

Reactant 3

HCID 1232383-AminoquinuclidineHCID 5460307FumarateHCID 12583440HCID 12583440, compound

Product 1

HCID 15616385HCID 15616385, compound

Procedure

The above compound was prepared, following the procedure of Example 1, from 3-aminoquinuclidine (0.63 g, 5 mmol) and crude 2-ethoxybenzoyl isocyanate (1.59 g, ca 7 mmol). The product (1.77 g) was converted to the 1:1 fumarate, mp 198°-199° C.

Workup

  1. customThe above compound was prepared

Sources & evidence

ORD record
ord-51dfe796cb0a44469d27e74db05d19e4
Source dataset
uspto-grants-1991_01
Patent number
US04983600

Reaction notes

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