3-Aminoquinuclidine → HCID 15616387, compound

HRID 703419Notes

Reaction equation

HRID 703419 reaction equation
[NH2:1][CH:2]1[CH:7]2[CH2:8][CH2:9][N:4]([CH2:5][CH2:6]2)[CH2:3]1.[CH2:10]([O:13][C:14]1[CH:24]=[CH:23][CH:22]=[CH:21][C:15]=1[C:16]([N:18]=[C:19]=[O:20])=[O:17])[CH:11]=[CH2:12].C([O-])(=O)/C=C/C([O-])=O>>[CH2:10]([O:13][C:14]1[CH:24]=[CH:23][CH:22]=[CH:21][C:15]=1[C:16]([NH:18][C:19]([NH:1][CH:2]1[CH:7]2[CH2:8][CH2:9][N:4]([CH2:5][CH2:6]2)[CH2:3]1)=[O:20])=[O:17])[CH:11]=[CH2:12]

Participants

4

Reactant 3

HCID 1232383-AminoquinuclidineHCID 5460307FumarateHCID 19820430HCID 19820430, compound

Product 1

HCID 15616387HCID 15616387, compound

Procedure

The above compound was prepared, following the procedure of Example 1, from 3-aminoquinuclidine (0.28 g, 2.2 mmol) and 2-allyloxybenzoyl isocyanate (0.53 g, ca 2.2 mmol). The product (0.61 g) was converted to the 1:1 fumarate.

Workup

  1. customThe above compound was prepared

Sources & evidence

ORD record
ord-ed65e30381ee4c26b40292547ca808d2
Source dataset
uspto-grants-1991_01
Patent number
US04983600

Reaction notes

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