反应详情

To a solution of 136.8 g of 3-methoxy-1-tetradecylbenzene in 600 ml of methylene chloride, cooled to -78° C., under inert gas, was added dropwise a solution of 112.8 g of boron tribromide in 100 ml of methylene chloride. The mixture was kept at -78° C. for 1 hour then allowed to warm slowly to room temperature followed by stirring for 16 hours. The mixture was cooled to 0° C. and cold water added dropwise. The organic layer was separated and washed with aqueous sodium bicarbonate, dried and the solvent evaporated. The residue was poured onto crushed ice and 107 g of the desired product collected as a white solid, m.p. 38°-40° C.

1. temperatureThe mixture was cooled to 0° C.
2. customThe organic layer was separated
3. washwashed with aqueous sodium bicarbonate
4. customdried
5. customthe solvent evaporated
6. additionThe residue was poured
7. customonto crushed ice and 107 g of the desired product
8. customcollected as a white solid, m.p. 38°-40° C.