HCID 20079503, compound → HCID 15053112, compound

Participants

Reaction Steps

A suspension of 1-methyl-N-(4-nitro-3-pyridinyl)-1H-indol-5-amine, N5 -oxide (6.8 g) in 250 ml ethanol containing 0.4 g platinum oxide was hydrogenated at 50 psi for twenty hours and thereafter filtered through Celite and concentrated to 3.5 g oil. This oil was purified by HPLC (silica 20% methanol in ethyl acetate) to give 2.5 g solid, m.p. 167°-169°. This solid was recrystallized from acetonitrile/ether to give 1.1 g solid, m.p. 168°-169°.

Provenance & Evidence