Ethyl 5-methylisoxazole-4-carboxylate → 5-Methylisoxazole-4-carboxylic acid

HRID 703506Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 703506
[CH3:1][C:2]1[O:6][N:5]=[CH:4][C:3]=1[C:7]([O:9]CC)=[O:8]>Cl>[CH3:1][C:2]1[O:6][N:5]=[CH:4][C:3]=1[C:7]([OH:9])=[O:8]

Komponenten

3

Edukt 1

HCID 7009317Ethyl 5-methylisoxazole-4-carboxylate

Produkt 1

HCID 14252405-Methylisoxazole-4-carboxylic acidAusbeute 78,9 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 313Hydrochloric AcidLösungsmittel

Versuchsvorschrift

Ethyl 5-methylisoxazol-4-yl carboxylate (65 g) was heated under reflux in 10 M HCl (500 ml) for 3 hours. On cooling the product crystallised out. This was filtered and dried giving 42 g of a white crystalline solid, m.p. 134°-136° C.

Aufarbeitung

  1. temperatureOn cooling the product
  2. customcrystallised out
  3. filtrationThis was filtered
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-9e61e1831a2a4d26804232aeaf16e09d
Quelldatensatz
uspto-grants-1991_01
Patentnummer
US04983619

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