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Benzyl Alcohol → 3-Butenoic acid, phenylmethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl Alcohol | HCID 244 | — |
| 反応物 | Triphenylphosphine | HCID 11776 | — |
| 反応物 | 3-Butenoic acid | HCID 32743 | — |
| 反応物 | N-ethoxycarbonyliminocarbamate | HCID 86599450 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 3-Butenoic acid, phenylmethyl ester | HCID 11019385 | — |
反応手順
138 g (535 mmol) Triphenylphosphine and 84 ml (812 mmol) benzyl alcohol were added dropwise to 46 g (535 mmol) 3-butenoic acid dissolved in 500 ml ether and 87 ml (535 mmol) ethyl azodicarboxylate and the mixture stirred for 7 hours and allowed to stand overnight. After evaporation of the solvent, the residue was purified by column chromotography (silica gel, hexane/ethyl acetate=95:5) and a sample analysed by thin layer chromatography (hexane:ethyl acetate=1:1) (Rf=0.61).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04983630 |
| 出典データセット | uspto-grants-1991_01 |
| ORD ID | ord-6c7c23e3bc6448038f06ec920c0cad30 |
| 出典メモ | uspto-grants-1991_01 |