HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzofuran-2-sulfonyl chloride → N-(5-chloro-2-{[(1-propyl-1H-imidazol-4-yl)methyl]thio}phenyl)-1-benzofuran-2-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzofuran-2-sulfonyl chloride | HCID 2795172 | — |
| Reactant | 5-chloro-2-(((1-propyl-1H-imidazol-4-yl)methyl)thio)aniline | HCID 67972244 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-(5-chloro-2-{[(1-propyl-1H-imidazol-4-yl)methyl]thio}phenyl)-1-benzofuran-2-sulfonamide | HCID 67972567 | 48.1% |
Reaction Steps
Following General Procedure B, the title compound (463 mg, 48%) was prepared from 5-chloro-2-(((1-propyl-1H-imidazol-4-yl)methyl)thio)aniline (587 mg, 2.082 mmol) and benzofuran-2-sulfonyl chloride (451 mg, 2.082 mmol) in pyridine (10 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822530B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-262cf25e335b4918804c373a81b2799e |
| Source note | uspto-grants-2014_09 |