tetrahydro-3-hexyl-4-oxo-(R)-6-undecyl-2H-pyran-2-one → (3S,4S,6R)-3-Hexyltetrahydro-4-hydroxy-6-undecyl-2H-pyran-2-one

Participants

Reaction Steps

8 g of an isomer mixture of tetrahydro-3-hexyl-4-oxo-(R)-6-undecyl-2H-pyran-2-one are dissolved in 2 l of ethyl acetate and 3 g of PtO2 are added. The mixture is then hydrogenated (50) bar for 12 hours. The catalyst is filtered off and the solution is evaporated. After recrystallization there are obtained 7 g of (3S,4S,6R)-tetrahydro-3-hexyl-4 -hydroxy-6 undecyl-2H-pyran-2-one, m.p. 108°-109° C.

Provenance & Evidence