HRID703689

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID66666

1,2-Divinylbenzene

C10H10

结构：CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)O[Si](C)(C)C(C)(C)C

HCID11583592

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCC[C@H](O)C[C@@H]1OC(=O)[C@H]1CCCCCC

HCID9968521

(3S,4S)-3-Hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one

C22H42O3

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

1.23 g of (3S,4S)-4-[(S)-2-(tert-butyldimethylsiloxy)tridecyl]-3-hexyl-2-oxetanone are dissolved in 6 ml of methanol and heated to reflux with the addition of 1.05 g of DOWEX 50W-X8 (acidic cation exchanger based on polymeric divinylbenzene containing sulphonic acid residues). The ion exchanger is filtered off and the filtrate is evaporated. The residue is chromatographed on silica gel. After recrystallization from hexane there is obtained (3S,4S)-3-hexyl-4-[(S)-2-hydroxytridecyl]-2-oxetanone of melting point 63°-64° C.

WORKUP

后处理

temperatureheated
filtrationThe ion exchanger is filtered off
customthe filtrate is evaporated
customThe residue is chromatographed on silica gel
customAfter recrystallization from hexane