HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzofuran-2-sulfonyl chloride → N-(5-chloro-2-{[(2-fluoropyridin-3-yl)methyl]thio}phenyl)-1-benzofuran-2-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzofuran-2-sulfonyl chloride | HCID 2795172 | — |
| Reactant | 5-Chloro-2-(((2-fluoropyridin-3-yl)methyl)thio)aniline | HCID 67972622 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-(5-chloro-2-{[(2-fluoropyridin-3-yl)methyl]thio}phenyl)-1-benzofuran-2-sulfonamide | HCID 67972731 | 26.9% |
Reaction Steps
Following General Procedure B, the title compound (235 mg) was prepared from 5-chloro-2-(((2-fluoropyridin-3-yl)methyl)thio)aniline (522 mg, 1.948 mmol) and benzofuran-2-sulfonyl chloride (421 mg, 1.948 mmol) in pyridine (5 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822530B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-66a6ff0e5390408782f965af3a148adf |
| Source note | uspto-grants-2014_09 |