Water → HCID 20074904, compound

Participants

Reaction Steps

A mixture of 2,3-dihydro-1H-cyclopent a[b]benzofuran-1-one oxime (1.0g) and polyphosphoric acid (ca.2 ml) was heated at 110° for 5h. Water (100 ml) was added and the suspension was extracted with ethyl acetate (3×50 ml). The combined extracts were dried and evaporated to give a solid (ca.325 mg) which was purified by FCC eluting with System B (1:1) to give the title compound, m.p. 158°-161°.

Provenance & Evidence