HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 5-Fluoro-2-((3-nitrobenzyl)thio)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Benzene, 1-(bromomethyl)-3-nitro- | HCID 77568 | — |
| Reactant | 2-Amino-4-fluorobenzene-1-thiol | HCID 11105480 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-Fluoro-2-((3-nitrobenzyl)thio)aniline | HCID 43304416 | 97% |
Reaction Steps
Following General Procedure A, the title compound (460 mg, 97%) was prepared from 2-amino-4-fluorobenzenethiol (562 g, 3.93 mmol), 1-(bromomethyl)-3-nitrobenzene (566 mg, 2.62 mmol), K2CO3 (1.8 g, 13.10 mmol) in DMF (10 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822530B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-697136108b5845e3b32265b19abeb3d1 |
| Source note | uspto-grants-2014_09 |