HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 5-Chloro-2-((4-nitrobenzyl)thio)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Amino-4-chlorobenzenethiol | HCID 12000 | — |
| Reactant | 4-Nitrobenzyl bromide | HCID 66011 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-Chloro-2-((4-nitrobenzyl)thio)aniline | HCID 12618213 | 93.3% |
Reaction Steps
Following General Procedure A, the title compound (624 mg, 92%) was prepared from 2-amino-4-chlorobenzenethiol (555 mg, 3.10 mmol), 1-(bromomethyl)-4-nitrobenzene (490 mg, 2.268 mmol) and K2CO3 (1.3 g, 9.50 mmol) in DMF (20 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822530B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-9a5193f074ad4d269cbaf446534f7848 |
| Source note | uspto-grants-2014_09 |