反应详情

Methyl [1-(3-propylphenyl)hydrazino]acetate (700 mg) was dissolved in acetonitrile (10 ml) under nitrogen at room temperature. Methyl isocyanate (0.69 ml) was added to the solution which was then heated at 80° for 85 min. The solvent was removed in vacuo and the residue was dissolved in ether (10 ml). Hexane (20 ml) was added to precipitate a solid which was filtered off to give the title compound (677 mg), m.p. 76°-77°.

1. temperaturewas then heated at 80° for 85 min
2. customThe solvent was removed in vacuo
3. dissolutionthe residue was dissolved in ether (10 ml)
4. additionHexane (20 ml) was added
5. customto precipitate a solid which
6. filtrationwas filtered off