HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 703924Generated: October 31, 2026
Sodium Chloride → N-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)acetamide
https://huagongshe.com/reaction/703924
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Chloride | HCID 5234 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | HCID 14476476 | HCID 14476476 | — |
| Product | N-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)acetamide | HCID 14476477 | — |
Reaction Steps
23.2 g. (0.1 mole) N-acetyl-3-(3,3-dimethylacryloylamino)-aniline, 92.8 g. aluminium chloride and 60 g. sodium chloride are well mixed up and heated to 100° C. for 2 hours. Thereafter, the reaction mixture is mixed with ice, briefly stirred and the crystallisate filtered off with suction. Yield 21.4 g. (92% of theory); m.p. 273°-278° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04985448 |
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| Source dataset | uspto-grants-1991_01 |
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| ORD ID | ord-414b3a775c394981a0f678b7579772b8 |
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| Source note | uspto-grants-1991_01 |
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