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Hexane → N-(1-Methoxy-2-methylpropylidene)-3-(2-chlorophenyl)-1,2,4-thiadiazole-5-sulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hexane | HCID 8058 | — |
| 反応物 | 1,1,1-Trimethoxy-2-methylpropane | HCID 40495 | — |
| 反応物 | 3-(2-Chlorophenyl)-1,2,4-thiadiazole-5-sulfonamide | HCID 14183136 | — |
| 生成物 | N-(1-Methoxy-2-methylpropylidene)-3-(2-chlorophenyl)-1,2,4-thiadiazole-5-sulfonamide | HCID 54055981 | — |
反応手順
A mixture of 2.9 g of 3-(2-chlorophenyl)-1,2,4-thiadiazole-5-sulfonamide in 11 ml of trimethyl orthoisobutyrate was warmed to about 85° with an oil bath. After 2.5 hours the solution was cooled to room temperature, whereupon a precipitate formed. Hexane (25 ml) was added to insure complete precipitation. The solid was filtered, washed with hexane and vacuum dried (P2O5) to give 3.08 g of solid, m.p. 75°-76°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04985450 |
| 出典データセット | uspto-grants-1991_01 |
| ORD ID | ord-e3f2e8b5ade74948b2b07f5b9bf1d2db |
| 出典メモ | uspto-grants-1991_01 |