Trifluoroacetic acid water → Mannitol
Reaction equation
F[C:2](F)(F)[C:3]([OH:5])=O.[OH2:8]>C(O)C>[CH2:3]([OH:5])[C@H:2]([C@H:3]([C@@H:2]([C@@H:2]([CH2:3][OH:5])[OH:8])[OH:8])[OH:5])[OH:8]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
In a second step the treatment of 0.5 g (0.4 mmol) of the intermediate product 40 dissolved in 4 ml of ethyl alcohol by a trifluoroacetic acid-water mixture (5/1 v/v) yields 0.32 g (70%) of 3,4-di-O-|3'-(F-octyl)-propanoyl|-D-mannitol, 41.
Sources & evidence
- ORD record
- ord-c4ee450e3a134a8fa66fe73b9e7d3246
- Source dataset
- uspto-grants-1991_01
- Patent number
- US04985550
Reaction notes
Loading…