2,4-Difluorobenzenesulfonyl Chloride → HCID 57378875, compound

HRID 70412Notes

Reaction equation

HRID 70412 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH3:10])=[C:6]([NH2:8])[CH:7]=1.[F:11][C:12]1[CH:17]=[C:16]([F:18])[CH:15]=[CH:14][C:13]=1[S:19](Cl)(=[O:21])=[O:20]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH3:10])=[C:6]([NH:8][S:19]([C:13]2[CH:14]=[CH:15][C:16]([F:18])=[CH:17][C:12]=2[F:11])(=[O:21])=[O:20])[CH:7]=1

Participants

3

Reactant 2

HCID 27342732,4-Difluorobenzenesulfonyl ChlorideHCID 27945775-Chloro-2-(methylthio)aniline

Product 1

HCID 57378875HCID 57378875, compoundYield 94%

Procedure

Following General Procedure B, the title compound (358 mg, 94%) was prepared from 5-chloro-2-methylsulfanyl-phenylamine (189 mg, 1.09 mmol) and 2,4-Difluoro-benzenesulfonyl chloride (231 mg, 1.09 mmol).

Sources & evidence

ORD record
ord-e0a638eae2c64bb897660c7c8792a7bc
Source dataset
uspto-grants-2014_09
Patent number
US08822530B2

Reaction notes

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