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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 70417Generated: October 25, 2026

2-Amino-4-chlorobenzenethiol → 4-chloro-N-{5-chloro-2-[(1H-imidazol-2-ylmethyl)thio]phenyl}-3-(trifluoromethyl)benzenesulfonamide

https://huagongshe.com/reaction/70417

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-4-chlorobenzenethiolHCID 12000—
Reactant2-(chloromethyl)-1H-imidazoleHCID 425763—
Reactant4-Chloro-3-(trifluoromethyl)benzenesulfonyl ChlorideHCID 2780719—
Product4-chloro-N-{5-chloro-2-[(1H-imidazol-2-ylmethyl)thio]phenyl}-3-(trifluoromethyl)benzenesulfonamideHCID 57377344—

Reaction Steps

Following General Procedure A, B, the title compound was prepared from 2-Amino-4-chloro-benzenethiol, 2-chloromethyl-1H-imidazole and 4-chloro-3-trifluoromethyl-benzenesulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08822530B2
Source datasetuspto-grants-2014_09
ORD IDord-10fca826ed6a42e78161d8e7bf708481
Source noteuspto-grants-2014_09