1-Benzofuran-2-sulfonyl chloride → HCID 67972727, compound

HRID 70423Notes

Reaction equation

HRID 70423 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([S:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-:20])=[O:19])[CH:13]=2)=[C:7]([CH:9]=1)[NH2:8].[O:21]1[C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=2[CH:23]=[C:22]1[S:30](Cl)(=[O:32])=[O:31]>N1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([S:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-:20])=[O:19])[CH:13]=2)=[C:7]([NH:8][S:30]([C:22]2[O:21][C:25]3[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=3[CH:23]=2)(=[O:31])=[O:32])[CH:9]=1

Participants

4

Reactant 2

HCID 27951721-Benzofuran-2-sulfonyl chlorideHCID 67972358HCID 67972358, compound

Product 1

HCID 67972727HCID 67972727, compoundYield 56%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Following General Procedure B, the title compound (406 mg, 56%) was prepared from 5-methoxy-2-((3-nitrobenzyl)thio)aniline (450 mg, 1.552 mmol) and benzofuran-2-sulfonyl chloride (335 mg, 1.552 mmol) in pyridine (5 ml).

Sources & evidence

ORD record
ord-c546bf9e517944c7ac298fd2ac810837
Source dataset
uspto-grants-2014_09
Patent number
US08822530B2

Reaction notes

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