HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 704263Generated: October 29, 2026
1,1'-(Diazomethylene)bis(benzene) → Benzhydryl 7-formamido-3-methylenecepham-4-carboxylate
https://huagongshe.com/reaction/704263
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,1'-(Diazomethylene)bis(benzene) | HCID 61230 | — |
| Reactant | 7-Formamido-3-methylenecepham-4-carboxylic acid | HCID 86743418 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Benzhydryl 7-formamido-3-methylenecepham-4-carboxylate | HCID 86744523 | — |
Reaction Steps
7-Formamido-3-methylenecepham-4-carboxylic acid (1.570 g) was added to a solution (0.93M, 8.36 l) of diphenyldiazomethane in ethyl acetate by portions. The mixture was stirred at 45° C. for 1 hour and evaporated in vacuo. The residue was triturated with diisopropyl ether to give benzhydryl 7-formamido-3-methylenecepham-4-carboxylate (2.337 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04985555 |
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| Source dataset | uspto-grants-1991_01 |
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| ORD ID | ord-08a1f09d86bb4ecaa822833e53064ef5 |
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| Source note | uspto-grants-1991_01 |
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