tert-Butyldimethylsilyl chloride → HCID 15729644, compound

HRID 704323Notes

Reaction equation

HRID 704323 reaction equation
[CH3:1][NH:2][S:3]([C:6]1[NH:7][C:8](=[O:12])[CH:9]=[CH:10][CH:11]=1)(=[O:5])=[O:4].[CH3:13][Si:14]([CH3:20])([C:16]([CH3:19])([CH3:18])[CH3:17])Cl>>[CH3:1][NH:2][S:3]([C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][Si:14]([CH3:20])([CH3:13])[C:16]([CH3:19])([CH3:18])[CH3:17])[N:7]=1)(=[O:5])=[O:4]

Participants

3

Reactant 2

HCID 28928tert-Butyldimethylsilyl chlorideHCID 20074196HCID 20074196, compound

Product 1

HCID 15729644HCID 15729644, compound

Procedure

2-(N-methylsulphamoyl)pyrid-6-one was silylated with dimethyl-(1,1-dimethylethyl)chlorosilane in the presence of imadazole under standard conditions to give 2-[N-methylsulphamoyl]-6-[dimethyl-(1,1-dimethylethyl)silyloxy]pyridine

Sources & evidence

ORD record
ord-e5793f0c820d427280757bc9250386aa
Source dataset
uspto-grants-1991_01
Patent number
US04987141

Reaction notes

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