Triethylamine → HCID 15729653, compound

Participants

Reaction Steps

2,6-dihydroxypyridine hydrochloride (3 g) was suspended in dichloromethane (250 cm3) under an atmosphere of nitrogen at 0° C. The mixture was treated with methanesulphonyl chloride (3.5 cm3). The suspension was stirred and triethylamine (9.4 cm3) was added in aliquots over 15 minutes. The resulting mixture was stirred for 17 hours and poured onto brine. The organic layer was separated, washed twice with brine, dried over anhydrous magnesium sulphate, and the solvent evaporated under reduced pressure.

Provenance & Evidence