L-(+)-Cysteine → 2-(3-Quinolyl)thiazolidine-4-carboxylic acid

Participants

Reaction Steps

Quinoline-3-carbaldehyde (1.57 g ) and 1.21 g of L-cysteine were dissolved in 50 ml of 50% ethanol, and the solution was stirred at room temperature for 1 hour. The resultant crystalline precipitate was collected by suction filtration, washed with 50% ethanol and dried to give 1.95 g of 2-(3-quinolyl)thiazolidine-4-carboxylic acid. Melting point 173°-175° C. (decomposition).

Provenance & Evidence