HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → Flumiclorac-pentyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3,4,5,6-Tetrahydrophthalic anhydride | HCID 12475 | — |
| Reactant | 4-Chloro-2-fluoro-5-(pentyloxycarbonylmethyloxy)aniline | HCID 14617850 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | Flumiclorac-pentyl | HCID 443048 | 92.3% |
Reaction Steps
A mixture of the compound (II) (12.0 g), 3,4,5,6-tetrahydrophthalic anhydride (7.56 g), triethylamine (9.42 g), acetic acid (0.75 g) and 1,2-dichloroethane (24 g) was heated under reflux for 8 hours. The reaction mixture was washed with water (24 g). The organic layer was separated and treated as in Example 4 to give the compound (I) (16.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04987247 |
| Source dataset | uspto-grants-1991_01 |
| ORD ID | ord-9bbaa1f07f2944a6a9bdb8297bcaf8c3 |
| Source note | uspto-grants-1991_01 |