HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → Flumiclorac-pentyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | 3,4,5,6-Tetrahydrophthalic anhydride | HCID 12475 | — |
| Reactant | 4-Chloro-2-fluoro-5-(pentyloxycarbonylmethyloxy)aniline | HCID 14617850 | — |
| Catalyst | p-Toluenesulfonic acid | HCID 6101 | — |
| Solvent | Water | HCID 962 | — |
| Product | Flumiclorac-pentyl | HCID 443048 | 88.9% |
Reaction Steps
A mixture of the compound (II) (12.0 g), 3,4,5,6-tetrahydrophthalic anhydride (7.56 g), p-toluenesulfonic acid (0.4 g) and toluene (24 g) was refluxed for 10 hours, during which water was azeotropically removed. The reaction mixture was treated in the same manner as in Example 4 to give the compound (I) (15.6 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04987247 |
| Source dataset | uspto-grants-1991_01 |
| ORD ID | ord-7851570c2d754afc87f0e32909610288 |
| Source note | uspto-grants-1991_01 |