HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 131716764, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-Pyrrolidinopyridine | HCID 75567 | — |
| Reactant | L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- | HCID 77857 | — |
| Reactant | HCID 14697649 | HCID 14697649 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 131716764 | HCID 131716764 | 111.3% |
Reaction Steps
A mixture of 2.4 g of the product of Step D, 40 ml of methylene chloride, 2.26 g (8.5 mmoles) of BOC-L-phenylalanine, 1.8 g (9.4 mmoles) of dicyclohexycarbodiimide and 1.26 g (8.5 mmoles) of 4-pyrrolidinopyridine was stirred for 16 hours. The mixture was poured into 100 ml of hydrochloric acid and the decanted organic phase was washed three times with water. After drying, the solvent was eliminated to obtain 5 g of a yellowish foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04988692 |
| Source dataset | uspto-grants-1991_01 |
| ORD ID | ord-1ef8ebc16b1b48e38fcd6619c0cea796 |
| Source note | uspto-grants-1991_01 |