HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 704627Generated: October 31, 2026
Pyridine → 1-[2-(2,3-Dihydro-3,3-dimethyl-2-oxoindol-5-yl)-2-oxoethyl]pyridinium chloride
https://huagongshe.com/reaction/704627
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 5-(2-chloroacetyl)-3,3-dimethyl-2,3-dihydro-1H-indol-2-one | HCID 10752379 | — |
| Product | 1-[2-(2,3-Dihydro-3,3-dimethyl-2-oxoindol-5-yl)-2-oxoethyl]pyridinium chloride | HCID 20072880 | — |
Reaction Steps
To 5-chloroacetyl-2,3-dihydro-3,3-dimethylindol-2-one (35 g) was added pyridine (140 ml) and the mixture was stirred to 1.6 hours at 85° C. After the mixture was cooled to ambient temperature, the crystal was collected by filtration and washed with pyridine and diethyl ether successively to give 1-[2-(2,3-dihydro-3,3-dimethyl-2-oxoindol-5-yl)-2-oxoethyl]pyridinium chloride (44.6 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04988698 |
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| Source dataset | uspto-grants-1991_01 |
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| ORD ID | ord-e335379dc56f4bdd96ff1fd879934fbf |
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| Source note | uspto-grants-1991_01 |
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