Methanol → HCID 53769624, compound

Participants

Reaction Steps

To a stirred solution of 176 mg (0.78 mmol) of the product of Example 16 in 10 mL of acetonitrile is added 0.287 mL (2.06 mmol) of triethylamine (TEA), 7 mg (0.0585 mmol) of 4-dimethylaminopyridine (DMAP) 0.177 mL (1.87 mmol) of acetic anhydride. After 3 h at ambient temperature, the clear solution is treated with 1 mL of methanol and concentrated under reduced pressure. The residue is purified by column chromatography on silica gel to afford the title compound.

Provenance & Evidence