HCID 15159550, compound → HCID 15159551, compound

Participants

Reaction Steps

To a dichloromethane solution (210 ml) of 1-[3,4-bis(p-methoxybenzyloxy)benzyl]-3-diphenylmethoxy-6-hydroxymethyl-4-pyridone (0.462 g) is added active manganese dioxide (2.40 g), and the mixture is stirred at room temperature for 20 minutes. Insolubles are removed by filtration, the filtrate is subjected to flash column chromatography on 50 g of Wako-Gel C-300 (manufactured by Wako Pure Chemical Industries, Ltd.) with an eluent of chloroform-methanol (20:1) to perform separation and purification. The title compound (0.264 g) is thus obtained as colorless crystal.

Provenance & Evidence