Butyric Acid → Propyl butyrate
Reaction equation
O[C:2]1[C:11]2C(=C(C(F)(F)F)C=CC=2)N=C(C(O)CC)[C:3]=1C(NC1SC=CN=1)=O.[C:28]([OH:33])(=[O:32])[CH2:29][CH2:30][CH3:31]>>[C:28]([O:33][CH2:3][CH2:2][CH3:11])(=[O:32])[CH2:29][CH2:30][CH3:31]Participants
3
Procedure
Using the procedure of Example5, 8 g of 4-hydroxy-2(1-hydroxypropyl)-N-(2-thiazolyl)-8-trifluoromethyl-3-quinoline carboxamide and 2 ml of butyric acid were reacted to obtain 7.8 g of 1-[4-hydroxy 3-[(2-thiazolylamino)-carboxyl]-8-trifluoromethyl)-2quinolinyl]-propyl butanoate melting at 203° C.
Workup
- customwere reacted
Sources & evidence
- ORD record
- ord-fb02dfdfe80b49fbb572cfea0be3e58b
- Source dataset
- uspto-grants-1991_01
- Patent number
- US04988708
Reaction notes
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