HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 3-(Oxiran-2-yl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Benzyl [2-(4-hydroxyphenyl)ethyl]carbamate | HCID 14103856 | — |
| Reactant | HCID 15067105 | HCID 15067105 | — |
| Reactant | HCID 20073190 | HCID 20073190 | — |
| Reactant | Benzyl [p-(2-ethoxyethoxy)]phenethylcarbamate | HCID 54264530 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(Oxiran-2-yl)pyridine | HCID 13319561 | — |
Reaction Steps
from 1.3 g of p-(2-ethoxyethoxy)-phenethylamine (prepared by the reaction of N-carbobenzoxytyramine in DMSO in the presence of potassium hydroxide with ethoxyethyl methanesulfonate and catalytic hydrogenation of the benzyl [p-(2-ethoxyethoxy)]phenethylcarbamate obtained in methanol in the presence of pd/C) and 726 mg of 3-[(RS)-2-oxiranyl]pyridine there were obtained
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04988714 |
| Source dataset | uspto-grants-1991_01 |
| ORD ID | ord-12b4ae10d71143e99f23b6e5bce018cb |
| Source note | uspto-grants-1991_01 |