HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → N-2-(4-(2-Pyrimidinyl)-1-piperazinyl)ethyl-1-methylcyclohexylcarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Methylcyclohexanecarbonyl chloride | HCID 4189245 | — |
| Reactant | 1-Piperazineethanamine, 4-(2-pyrimidinyl)- | HCID 13885358 | — |
| Product | N-2-(4-(2-Pyrimidinyl)-1-piperazinyl)ethyl-1-methylcyclohexylcarboxamide | HCID 14801917 | — |
Reaction Steps
The title compound was prepared from 2-(4-(2-pyrimidinyl)-1-piperazinyl)ethyl amine (1.50 g, 0.00724 mol), 1-methylcyclohexylcarboxylic acid chloride (1.16 g, 0.00722 mol) and triethylamine (1.1 mL, 0.80 g, 0.0079 mol) in the manner previously described to give 1.80 g (62%) of product, mp. 212°-220° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04988814 |
| Source dataset | uspto-grants-1991_01 |
| ORD ID | ord-343061f1fa8348f9a1170f0e302ca1ff |
| Source note | uspto-grants-1991_01 |