HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66854350, compound → HCID 49869551, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66854350 | HCID 66854350 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 49869551 | HCID 49869551 | 59.6% |
Reaction Steps
(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one (0.5 g, 1.857 mmol) was added to methanol (50 ml) to give a yellow solution. Palladium on carbon (0.05 g) was added. Product was hydrogenated while stirring till conversion was completed (checked by TLC). The reaction mixture was filtered, evaporated and the solid residue was washed with diethylether, and dried to yield 0.3 g (57%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09173424B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-9224b33b097a4dfc9e90a7776e8d074b |
| Source note | uspto-grants-2015_11 |