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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 704964Generated: October 31, 2026

HCID 66854350, compound → HCID 49869551, compound

https://huagongshe.com/reaction/704964

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66854350HCID 66854350—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 49869551HCID 4986955159.6%

Reaction Steps

(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one (0.5 g, 1.857 mmol) was added to methanol (50 ml) to give a yellow solution. Palladium on carbon (0.05 g) was added. Product was hydrogenated while stirring till conversion was completed (checked by TLC). The reaction mixture was filtered, evaporated and the solid residue was washed with diethylether, and dried to yield 0.3 g (57%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09173424B2
Source datasetuspto-grants-2015_11
ORD IDord-9224b33b097a4dfc9e90a7776e8d074b
Source noteuspto-grants-2015_11