Ethyl bromoacetate → HCID 70497294, compound

Participants

Reaction Steps

To 2-amino-5-fluoro pyridine (2.0 g, 17.84 mmol) was added ethyl bromoacetate (6.92 mL, 62.4 mmol). The resulting mixture was stirred at room temperature for 18 hours, then filtered. The solids were collected, washed with dichloromethane, and dried under reduced pressure to afford the title compound: LCMS m/z 199.00 [M+H]+; 1H NMR (500 MHz, CD3OD) δ 8.05 (s, 1H), 7.93-7.90 (m, 1H), 7.14-7.12 (m, 1H), 5.02 (s, 2H), 4.25 (t, J=7.1 Hz, 2H), 1.27 (q, J=7.1 Hz, 3H).

Provenance & Evidence