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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 70507Generated: October 30, 2026

HCID 67396693, compound → 5-Cyclopropyl-6-methoxypyridine-2-carbaldehyde

https://huagongshe.com/reaction/70507

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67396693HCID 67396693—
CatalystHCID 178418406HCID 178418406—
SolventChloroformHCID 6212—
Product5-Cyclopropyl-6-methoxypyridine-2-carbaldehydeHCID 8665799985%

Reaction Conditions

Temperature65 °C

Reaction Steps

Manganese dioxide (67 g) was added to a solution of (5-cyclopropyl-6-methoxypyridin-2-yl)methanol (14.1 g) in chloroform (200 mL), and the mixture was stirred at 65° C. for one hour. The reaction solution was filtered through celite and the filtrate was concentrated to give 5-cyclopropyl-6-methoxypyridine-2-carbaldehyde (11 g, 85%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08822503B2
Source datasetuspto-grants-2014_09
ORD IDord-f93c0b8c71f24745bb72eba7f3fd6efa
Source noteuspto-grants-2014_09