HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → 3-Amino-6-(2,6-difluorophenyl)-5-fluoropicolinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | Methyl 3-amino-6-(2,6-difluorophenyl)-5-fluoropicolinate | HCID 59226608 | — |
| Product | 3-Amino-6-(2,6-difluorophenyl)-5-fluoropicolinic acid | HCID 59226513 | 79% |
Reaction Steps
Method 2 was followed using methyl 3-amino-6-(2,6-difluorophenyl)-5-fluoropicolinate (1.0 equiv.) and LiOH (1.0 equiv.) to give 3-amino-6-(2,6-difluorophenyl)-5-fluoropicolinic acid in 79% yield. LCMS (m/z): 269.0 (MH+), Rt=0.79 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09173883B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-95d3ce60c9904ca19a3455f175a064d9 |
| Source note | uspto-grants-2015_11 |