Methanol → HCID 22943903, compound

Participants

Reaction Steps

To a solution of racemic derivative Bisphenol A diglycidyl ether (500 mg, 1.46 mmol, 1 equiv) in methanol (5 mL) was added solid Erbium(III) trifluoromethanesulfonate (90 mg, 0.146 mmol, 1/10 equiv) in one portion and the mixture was stirred at room temperature for 1 h. Sodium bicarbonate was added (1 mL), the organic solvent was evaporated under reduced pressure and the residue was extracted with dichloromethane (3×5 mL). The organic layer was washed with deionized water (2×5 mL), was dried over anhydrous magnesium sulfate, was filtered, and was concentrated under reduced pressure. The resulting residue was purified by flash column chromatography on silica gel (eluent: 10% to 40% ethyl acetate in hexane) to provide the title compound (128 mg, 23%) as a pale foam.

Provenance & Evidence