反应详情

温度

82.5 °C

27.8 g of (2-butyl-5-nitro-1-benzofur-3-yl)-(4-hydroxyphenyl)methanon (VIII), 43.5 g of acrylonitrile and 3.8 g of Triton B (benzyltrimethylammonium hydroxide) are added and heated under stirring to 80-85° C. and stirred at this temperature for 48 hours. After cooling the reaction mixture to room temperature it is evaporated and the acrylonitrile is recovered for the next trial. To the residue 150 ml of dichloromethane is added and washed with 3×80 ml of sodium hydroxide of 5%. From the sodium hydroxide solution 16.2 g of starting (2-butyl-5-nitro-1-benzofur-3-yl)-(4-hydroxyphenyl)methanon is recovered.

1. temperatureheated
2. stirringstirred at this temperature for 48 hours
3. temperatureAfter cooling the reaction mixture to room temperature it
4. customis evaporated
5. customthe acrylonitrile is recovered for the next trial
6. additionTo the residue 150 ml of dichloromethane is added
7. washwashed with 3×80 ml of sodium hydroxide of 5%
8. customFrom the sodium hydroxide solution 16.2 g of starting (2-butyl-5-nitro-1-benzofur-3-yl)-(4-hydroxyphenyl)methanon is recovered