反应详情

0.4 mL of 3-chloroaniline was slowly added to 4 mL of a fuming sulfuric acid and stirred at room temperature overnight. Cooling it down to 0° C., the reaction solution was poured in water, and a precipitated solid substance was taken by filtration. The solid substance was dissolved in an aqueous solution of 2N sodium hydroxide. Then, a concentrated hydrochloric acid wad added thereto to make the liquid acidic. The precipitated solid substance was filtered out to obtain a crude product of 4-amino-2-chlorobenzenesulfonic acid.

1. temperatureCooling it down to 0° C.
2. filtrationa precipitated solid substance was taken by filtration
3. dissolutionThe solid substance was dissolved in an aqueous solution of 2N sodium hydroxide
4. additionThen, a concentrated hydrochloric acid wad added
5. filtrationThe precipitated solid substance was filtered out