Iodine → HCID 11392086, compound

Participants

Reaction Conditions

Reaction Steps

To a stirred solution of N-boc-1,4-phenylene diamine (13.33 g, 63.9mmol) in mesityl oxide (40ml, 367mmol), under an N2 atmosphere, was added iodine (3.47 g, 12.8 mmol) portionwise over 5minutes. The reaction was stirred at 100° C. for 3 hours, then cooled to ambient temperature and reduced to yield the title compound as a crude brown oil (18.4 g, 100%). The product was used without further purification.

Provenance & Evidence