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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 706168Generated: October 31, 2026

3-Methoxyphenol → 4-Hydroxy-8-(3-methoxy-phenoxy)-isoquinoline-3-carboxylic acid methyl ester

https://huagongshe.com/reaction/706168

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxyphenolHCID 9007—
ReactantMethyl 4-hydroxy-8-iodoisoquinoline-3-carboxylateHCID 67110147—
Product4-Hydroxy-8-(3-methoxy-phenoxy)-isoquinoline-3-carboxylic acid methyl esterHCID 67110364—

Reaction Steps

The title compound was synthesized from 4-hydroxy-8-iodo-isoquinoline-3-carboxylic acid methyl ester and 3-methoxy-phenol in analogy to example 19d; MS-(+)-ion: M+1=326.4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09174976B2
Source datasetuspto-grants-2015_11
ORD IDord-a294570fa62d4fedb6fb02cd91688123
Source noteuspto-grants-2015_11