4-Fluorophenol → 2-(4-Fluoro-phenoxy)-6-methyl-benzoic acid

HRID 706179Notes

Reaction equation

HRID 706179 reaction equation
Cl[C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=1[C:4]([OH:6])=[O:5].[F:12][C:13]1[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=1>>[F:12][C:13]1[CH:18]=[CH:17][C:16]([O:19][C:2]2[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=2[C:4]([OH:6])=[O:5])=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 97324-FluorophenolHCID 888702-Chloro-6-methylbenzoic acid

Product 1

HCID 671102182-(4-Fluoro-phenoxy)-6-methyl-benzoic acid

Procedure

The title compound was synthesized from 2-chloro-6-methyl-benzoic acid and 4-fluorophenol in analogy to example 18a; MS-(−)-ion: M−1=245.5.

Sources & evidence

ORD record
ord-4238798d89a149dfa9c5f2aeb53da1fe
Source dataset
uspto-grants-2015_11
Patent number
US09174976B2

Reaction notes

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