HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 2-(4-Fluoro-phenoxy)-6-{[methoxycarbonylmethyl-(toluene-4-sulfonyl)-amino]-methyl}-benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Methyl 2-(4-methylphenylsulfonamido)acetate | HCID 562880 | — |
| Reactant | 2-(4-Fluoro-phenoxy)-6-methyl-benzoic acid methyl ester | HCID 67110134 | — |
| Product | 2-(4-Fluoro-phenoxy)-6-{[methoxycarbonylmethyl-(toluene-4-sulfonyl)-amino]-methyl}-benzoic acid methyl ester | HCID 67110423 | — |
Reaction Steps
The crude title compound was synthesized from 2-(4-fluoro-phenoxy)-6-methyl-benzoic acid methyl ester, N-bromosuccinimide, and (toluene-4-sulfonylamino)-acetic acid methyl ester in analogy to example 18c and was used in the following step without further purification; MS-(+)-ion: M+23=524.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09174976B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-38d8589288ac4b55b1f00e1468835f5e |
| Source note | uspto-grants-2015_11 |