Glycine → HCID 24780415, compound

HRID 706192Notes

Reaction equation

HRID 706192 reaction equation
C(O[C:6]([C:8]1[N:9]=[C:10]([C:29]#[N:30])[C:11]2[C:16]([C:17]=1[OH:18])=[CH:15][C:14]([O:19][C:20]1[C:25]([CH3:26])=[CH:24][C:23]([Cl:27])=[CH:22][C:21]=1[CH3:28])=[CH:13][CH:12]=2)=[O:7])CCC.[NH2:31][CH2:32][C:33]([OH:35])=[O:34]>>[Cl:27][C:23]1[CH:24]=[C:25]([CH3:26])[C:20]([O:19][C:14]2[CH:15]=[C:16]3[C:11](=[CH:12][CH:13]=2)[C:10]([C:29]#[N:30])=[N:9][C:8]([C:6]([NH:31][CH2:32][C:33]([OH:35])=[O:34])=[O:7])=[C:17]3[OH:18])=[C:21]([CH3:28])[CH:22]=1

Participants

3

Reactant 2

HCID 750GlycineHCID 67110530HCID 67110530, compound

Product 1

HCID 24780415HCID 24780415, compound

Procedure

The title compound was synthesized from 6-(4-Chloro-2,6-dimethyl-phenoxy)-1-cyano-4-hydroxy-isoquinoline-3-carboxylic acid butyl ester and glycine in analogy to example 1b; MS-(−)-ion: M−1=424.3.

Sources & evidence

ORD record
ord-b0709a975c9048068b4e1cbc105d6c65
Source dataset
uspto-grants-2015_11
Patent number
US09174976B2

Reaction notes

Loading…