HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86617077, compound → HCID 67110118, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86617077 | HCID 86617077 | — |
| Reactant | HCID 178418546 | HCID 178418546 | — |
| Product | HCID 67110118 | HCID 67110118 | 49% |
Reaction Steps
Prepared from 6-benzenesulfonyl-1-bromo-4-hydroxy-isoquinoline-3-carboxylic acid butyl ester and CuCN in analogy to example 29a. Crude product was purified by silica gel chromatography (2%-20% ethyl acetate in methylene chloride) to give the title compound (49% yield). MS-(+)-ion: M+1=411.30.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09174976B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-5f25d0c13e424615baea0a8b933c255d |
| Source note | uspto-grants-2015_11 |