Glycine → HCID 24780550, compound

HRID 706209Notes

Reaction equation

HRID 706209 reaction equation
C(O[C:6]([C:8]1[N:9]=[C:10]([C:29]#[N:30])[C:11]2[C:16]([C:17]=1[OH:18])=[CH:15][CH:14]=[C:13]([O:19][C:20]1[CH:28]=[CH:27][C:23]3[O:24][CH2:25][O:26][C:22]=3[CH:21]=1)[CH:12]=2)=[O:7])CCC.[NH2:31][CH2:32][C:33]([OH:35])=[O:34]>>[O:24]1[C:23]2[CH:27]=[CH:28][C:20]([O:19][C:13]3[CH:12]=[C:11]4[C:16]([C:17]([OH:18])=[C:8]([C:6]([NH:31][CH2:32][C:33]([OH:35])=[O:34])=[O:7])[N:9]=[C:10]4[C:29]#[N:30])=[CH:15][CH:14]=3)=[CH:21][C:22]=2[O:26][CH2:25]1

Participants

3

Reactant 2

HCID 750GlycineHCID 67110126HCID 67110126, compound

Product 1

HCID 24780550HCID 24780550, compound

Procedure

Prepared in analogy to example 31h from 7-(benzo[1,3]dioxol-5-yloxy)-1-cyano-4-hydroxy-isoquinoline-3-carboxylic acid butyl ester and glycine. ESI MS (m/z): 406 (M−H)−.

Sources & evidence

ORD record
ord-9860cfd8ddc2412e925d0002515c4d14
Source dataset
uspto-grants-2015_11
Patent number
US09174976B2

Reaction notes

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