HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminobenzimidazole → HCID 178517663, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminobenzimidazole | HCID 13623 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 2-Amino-1-(4-fluorophenyl)ethan-1-one hydrochloride | HCID 13290666 | — |
| Product | HCID 178517663 | HCID 178517663 | — |
Reaction Steps
The compound was synthesized as hydrochloride salt starting from 5-aminobenzimidazole (0.665 g, 5 mmol), di(1H-imidazol-1-yl)methanone (0.891 g, 5.5 mmol), TEA (2.09 mL, 15 mmol), aminomethyl-(4-fluorophenyl)ketone hydrochloride (0.948 g, 5 mmol), TEA (1.39 mL, 10 mmol), PdC (10%, 0.02 g) as described in method 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09173885B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-d6189df91b15428cbeb45fd3ef64c338 |
| Source note | uspto-grants-2015_11 |