HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminobenzimidazole → HCID 178517665, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminobenzimidazole | HCID 13623 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | Trimethylsilyl cyanide | HCID 82115 | — |
| Reactant | 2-Fluoro-5-(trifluoromethyl)benzaldehyde | HCID 2734904 | — |
| Product | HCID 178517665 | HCID 178517665 | — |
Reaction Steps
The compound was synthesized from 2-fluoro-5-(trifluoromethyl)benzaldehyde (0.565 mL, 4 mmol), 5-aminobenzimidazole (0.585 g, 4.4 mmol), TMSCN (0.5 g, 4 mmol), TEA (0.669 mL, 4.8 mmol), PdC (10%, 0.02 g), di(1H-imidazol-1-yl)methanone (0.778 g, 4.8 mmol) as described in method 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09173885B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-8c3592ec9ca6450e84a198abd9310235 |
| Source note | uspto-grants-2015_11 |