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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 706321Generated: October 26, 2026

1,1'-Carbonyldiimidazole → HCID 178517619, compound

https://huagongshe.com/reaction/706321

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantTrimethylsilyl cyanideHCID 82115—
Reactantp-CyclohexylbenzaldehydeHCID 119689—
ReactantHCID 178507353HCID 178507353—
CatalystPalladiumHCID 23938—
ProductHCID 178517619HCID 178517619—

Reaction Steps

The compound was synthesized starting from 1H-benzo[d]imidazol-5-amine (0.400 g, 3 mmol), 4-cyclohexylbenzaldehyde (0.565 g, 3 mmol), TMSCN (0.375 mL, 3 mmol), Pd/C (10%, 0.02 g), TEA 1.05 mL, 7.5 mmol), di-(imidazol-1-yl)methanone (0.730 g, 4.5 mmol) as described in method 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09173885B2
Source datasetuspto-grants-2015_11
ORD IDord-dcd6ed5ef12e43718f607ab9fd00a05f
Source noteuspto-grants-2015_11